検索結果

Search Results for " AMP-activated protein kinase "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T8476	RSVA405	RSVA 405	AMPK , STAT , Autophagy
	RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor		AMPK , STAT , Autophagy
T2374	HTH-01-015		AMPK
	HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).		AMPK
T7362	O-304		AMPK
	O-304 is a pan-activator of AMP-activated protein kinase (AMPK).		AMPK
T6285	GSK-690693	GSK690693	Serine Protease , Akt , PKC , AMPK , Autophagy
	GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.		Serine Protease , Akt , PKC , AMPK , Autophagy
T16099	MK8722		AMPK
	MK8722 is an effective and systemic activator of pan-AMPK.		AMPK
T13411	ZLN024		AMPK
	ZLN024 is an activator of AMPK allosteric. ZLN024 allosterically stimulates active AMPK heterotrimers and the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).		AMPK
T6291	WZ4003		AMPK
	WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases.		AMPK
T5187	MK-3903	MK 3903	AMPK
	MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).		AMPK
T11947	MARK4 inhibitor 1		Apoptosis , Others , AMPK
	MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.		Apoptosis , Others , AMPK
T13173	TMPA		Others , AMPK
	TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.		Others , AMPK
T8740	COH-SR4	COH-SR4 (Mitochondria uncoupler SR4)	Others , AMPK
	COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation. COH-SR4 modulates amp-dependent kinase (ampk)-mammalian target of rapamycin (mtor) signaling, and inhibiting proli...		Others , AMPK
T4427	PF-06409577	PF 06409577	AMPK
	PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).		AMPK
T2468	A-769662	A 769662	AMPK , Fatty Acid Synthase
	A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).		AMPK , Fatty Acid Synthase
T8432	ASP4132		AMPK
	ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.		AMPK
T10789	Chitosan oligosaccharide	COS	AMPK
	Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. It has the ability to activate AMPK and simultaneously inhibit inflammatory signaling pathways, including NF-κB and MAPK.		AMPK
T3546	STO-609	STO 609	CaMK , AMPK , Autophagy
	STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL).		CaMK , AMPK , Autophagy
T41162	ZLN 024 hydrochloride		AMPK
	ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).		AMPK
T7955	EB-3D		Apoptosis , AMPK , AChR
	EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.		Apoptosis , AMPK , AChR
T6854	GSK621		Apoptosis , AMPK , Autophagy
	GSK621 is a specific and potent AMPK activator.		Apoptosis , AMPK , Autophagy
TQ0028	EX229	Compound 991,C991	AMPK
	EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.		AMPK
T6920	ON123300		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).		FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK
T1453	Phenformin hydrochloride	Phenformin HCl,Phenethylbiguanide hydrochloride	Potassium Channel , AMPK , Autophagy
	Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.		Potassium Channel , AMPK , Autophagy
T1477	AICAR	NSC105823,AICA Riboside,Acadesine,AICAR (Acadesine)	Mitophagy , YAP , AMPK , Autophagy
	AICAR (NSC105823) is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes.		Mitophagy , YAP , AMPK , Autophagy
T19659	Annaosanchun	YC6,YC-6,YC 6	Others , AMPK
	Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).		Others , AMPK
T8526	Metformin	1,1-Dimethylbiguanide	Mitophagy , AMPK , Autophagy
	Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm...		Mitophagy , AMPK , Autophagy
T16156	MT 63-78		Apoptosis , AMPK , mTOR
	MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cel...		Apoptosis , AMPK , mTOR
T3625	Bempedoic acid	ETC1002,ESP-55016,ETC 1002,ETC-1002	ATP Citrate Lyase , AMPK
	Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic ...		ATP Citrate Lyase , AMPK
T1977	Dorsomorphin	Compound C,BML-275	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...		AMPK , Autophagy , TGF-beta/Smad
T0858	Flufenamic acid	Arlef,Nichisedan,Achless	Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
	Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T20029	Buformin hydrochloride	NSC528218,NSC-528218,NSC 528218	AMPK
	Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and...		AMPK
T9010	IMM-H007		Others , AMPK
	IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression		Others , AMPK
T0740	Metformin hydrochloride	Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride	Mitophagy , AMPK , Autophagy
	Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells including colon, pro...		Mitophagy , AMPK , Autophagy
T8929	BC1618	2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-	Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
	BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and imp...		Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
T6146	Dorsomorphin dihydrochloride	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.		AMPK , Autophagy , TGF-beta/Smad
TP1760L	AMARA peptide acetate(163560-19-8 free base)		Others
	AMARA peptide acetate is a substrate for SIK and AMPK.AMARA peptide is a minimal substrate of several members of the protein kinases family. It consists of the phosphorylation site for AMP-activated Protein Kinase (AMPK)...		Others
T7535	RGX-202	β-GPA,3-Guanidinopropionic Acid	AMPK , PPAR
	RGX-202 (β-GPA) is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coac...		AMPK , PPAR
T36420	IM-156 acetate	HL271 acetate
	IM-156 acetate, an activator of NADH dehydrogenase (IC50=2.2 μM) and AMP-activated protein kinase alpha (AMPKα), is an orally available and bioavailable inhibitor of mitochondrial oxidative phosphorylation (OxPhos).IM-15...
T19661	8-Chloroadenosine	NSC 354258,8-Cl-Ado,NSC354258,NSC-354258	AMPK
	8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Ch...		AMPK
T70085	IND 1316
	IND 1316 is an activator of AMP-activated protein kinase (AMPK).
T71222	Metformin glycinate
	Metformin glycinate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
TP1812	SAMS
	SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).
T69405	Metformin embonate
	Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T69049	Metformin orotate
	Metformin orotate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T70806	Metformin icosapent
	Metformin icosapent is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T20028	Janumet	Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate
	Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator.
TP1760	AMARA peptide
	AMARA peptide is a substrate for SIK and AMPK.AMARA peptide is a minimal substrate of several members of the protein kinases family. It consists of the phosphorylation site for AMP-activated Protein Kinase (AMPK).
T83740	Ziptide TFA
	Ziptide, a peptide substrate, is recognized by several serine/threonine protein kinases, such as MAPK activated protein kinase 2 (MAPKAPK2), MAPKAPK3, MAPKAPK5, checkpoint kinase 1 (Chk1), AMP-activated protein kinase (A...
T73224	AMPK-IN-1
	AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM. It induces phosphorylation of eEF2 independent of the mTORC1 pathway.
T63177	AMPK activator 8
	AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator that acts on rAMPK α1β1γ1 (EC50: 11 nM), rAMPK α2β1γ1 (EC50: 27 nM), rAMPK α1β2γ1 (EC50: 4 nM), rAMPK α2β2 AMPK activator 8 can be used to...
T79226	AMPK activator 11		Mitochondrial Metabolism
	AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative...		Mitochondrial Metabolism

Compounds

RSVA405

T8476

Synonym: RSVA 405

Target: AMPK, STAT, Autophagy

Target: Serine Protease, Akt, PKC, AMPK, Autophagy

Target: Apoptosis, Others, AMPK

TMPA

T13173

Synonym:

Target: Others, AMPK

COH-SR4

T8740

Synonym: COH-SR4 (Mitochondria uncoupler SR4)

Target: Others, AMPK

Target: AMPK, Fatty Acid Synthase

Chitosan oligosaccharide

Target: CaMK, AMPK, Autophagy

ZLN 024 hydrochloride

Target: Apoptosis, AMPK, AChR

GSK621

T6854

Synonym:

Target: Apoptosis, AMPK, Autophagy

EX229

TQ0028

Synonym: Compound 991,C991

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

Phenformin hydrochloride

T1453

Synonym: Phenformin HCl,Phenethylbiguanide hydrochloride

Target: Potassium Channel, AMPK, Autophagy

AICAR

T1477

Synonym: NSC105823,AICA Riboside,Acadesine,AICAR (Acadesine)

Target: Mitophagy, YAP, AMPK, Autophagy

Annaosanchun

T19659

Synonym: YC6,YC-6,YC 6

Target: Others, AMPK

Metformin

T8526

Synonym: 1,1-Dimethylbiguanide

Target: Mitophagy, AMPK, Autophagy

MT 63-78

T16156

Synonym:

Target: Apoptosis, AMPK, mTOR

Bempedoic acid

T3625

Synonym: ETC1002,ESP-55016,ETC 1002,ETC-1002

Target: ATP Citrate Lyase, AMPK

Dorsomorphin

T1977

Synonym: Compound C,BML-275

Target: AMPK, Autophagy, TGF-beta/Smad

Flufenamic acid

T0858

Synonym: Arlef,Nichisedan,Achless

Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite

Buformin hydrochloride

T20029

Synonym: NSC528218,NSC-528218,NSC 528218

Target: Others, AMPK

Metformin hydrochloride

T0740

Synonym: Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride

Target: Mitophagy, AMPK, Autophagy

BC1618

T8929

Synonym: 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-

Target: Mitophagy, Others, E1/E2/E3 Enzyme, AMPK

Dorsomorphin dihydrochloride

T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

AMARA peptide acetate(163560-19-8 free base)

Synonym: β-GPA,3-Guanidinopropionic Acid

Target: AMPK, PPAR

IM-156 acetate

T36420

Synonym: HL271 acetate

Target:

8-Chloroadenosine

T19661

Synonym: NSC 354258,8-Cl-Ado,NSC354258,NSC-354258

Synonym: Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate

Target: Mitochondrial Metabolism

カタログ番号	製品名	別名	ターゲット
TN1828	Kahweol		Apoptosis , NF-κB , AMPK
	Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degradation and inhibiting IkappaB kinase activity.		Apoptosis , NF-κB , AMPK
T3889	Platycodin D		Prostaglandin Receptor , AMPK
	Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...		Prostaglandin Receptor , AMPK
TN1100	Nepodin		transporter , COX , AMPK , Parasite
	Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, which is at least partly mediated by stimulation of GLUT4 tra...		transporter , COX , AMPK , Parasite
T7327	7-Methoxyisoflavone		AMPK
	7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).		AMPK
T4S0800	Demethyleneberberine		P450 , NOS , NF-κB , HIF , AMPK
	Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1,...		P450 , NOS , NF-κB , HIF , AMPK
T3881	Vaccarin		Integrin , Akt , PERK , AMPK
	Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.		Integrin , Akt , PERK , AMPK
T3904	Gomisin J		Calcium Channel , AMPK
	Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...		Calcium Channel , AMPK
T5497	AMAROGENTIN		Apoptosis , AMPK
	Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis		Apoptosis , AMPK
T2S0820	Karanjin		Apoptosis , AMPK
	Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arre...		Apoptosis , AMPK
T3405	[6]-Gingerol	6-Gingerol,gingerol,(S)-(+)-[6]Gingerol	Apoptosis , AMPK
	[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other tissues.		Apoptosis , AMPK
TN1911	Marein		transporter , Akt , HDAC , AMPK
	Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ...		transporter , Akt , HDAC , AMPK
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
TN1499	Cimiracemoside C	Cimicifugoside M	AMPK
	Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.		AMPK
T19500	Palmitelaidic Acid	trans-Palmitoleic acid,9-trans-Hexadecenoic acid	Glucokinase , AMPK , PPAR
	Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.		Glucokinase , AMPK , PPAR
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T2750	Ginkgolide C	BN-52022	MMP , Sirtuin , Endogenous Metabolite , AMPK
	Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.		MMP , Sirtuin , Endogenous Metabolite , AMPK
T0800	Danthron	Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol	Virus Protease , Antibacterial , AMPK , Autophagy
	Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.		Virus Protease , Antibacterial , AMPK , Autophagy
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T1456	Doxorubicin	Hydroxydaunorubicin,Adriamycin	Topoisomerase , AMPK
			Topoisomerase , AMPK
T5S1172	Tiliroside	Tribuloside	Antioxidant
	1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati...		Antioxidant
T28021	Meso-Dihydroguaiaretic acid
	meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.

天然物製品

Kahweol

TN1828

Synonym:

Target: Apoptosis, NF-κB, AMPK

Platycodin D

T3889

Synonym:

Target: Prostaglandin Receptor, AMPK

Nepodin

TN1100

Synonym:

Target: transporter, COX, AMPK, Parasite

Target: P450, NOS, NF-κB, HIF, AMPK

Vaccarin

T3881

Synonym:

Target: Integrin, Akt, PERK, AMPK

Gomisin J

T3904

Synonym:

Target: Calcium Channel, AMPK

AMAROGENTIN

T5497

Synonym:

Target: Apoptosis, AMPK

Karanjin

T2S0820

Synonym:

Target: Apoptosis, AMPK

[6]-Gingerol

T3405

Synonym: 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol

Target: Apoptosis, AMPK

Marein

TN1911

Synonym:

Target: transporter, Akt, HDAC, AMPK

Methyl cinnamate

T5552

Synonym:

Target: Tyrosinase, Antibacterial, AMPK

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Cimiracemoside C

TN1499

Synonym: Cimicifugoside M

Target: AMPK

Palmitelaidic Acid

T19500

Synonym: trans-Palmitoleic acid,9-trans-Hexadecenoic acid

Target: Glucokinase, AMPK, PPAR

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Ginkgolide C

T2750

Synonym: BN-52022

Target: MMP, Sirtuin, Endogenous Metabolite, AMPK

Danthron

T0800

Synonym: Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol

Target: Virus Protease, Antibacterial, AMPK, Autophagy

Doxorubicin hydrochloride

T1020

Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127

Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy

Doxorubicin

T1456

Synonym: Hydroxydaunorubicin,Adriamycin

Target: Topoisomerase, AMPK

meso-Dihydroguaiaretic acid

T28021

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02481	PRKAG1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK a...
TMPH-02480	PRKAB1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK act...
TMPJ-00886	ATF1 Protein, Human, Recombinant (His)	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by r...
TMPY-04751	VRK1 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. Serine/threonine protein kinases are tumor suppressor that controls the activity of AMP-activated protein kinase family me...
TMPY-04560	VRK1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. Serine/threonine protein kinases are tumor suppressor that controls the activity of AMP-activated protein kinase family me...
TMPH-02478	PRKAA1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...
TMPH-02479	PRKAA1 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...